Michael Agus, MD
Harvard Medical School, Cambridge, Massachusetts, USA and Boston Children’s Hospital, Boston, Massachusetts

Dr. Agus is the Division Chief of Medical Critical Care within the Department of Pediatrics at Boston Children’s Hospital where he is the Founding Medical Director of the Medical Intensive Care Unit and the Intermediate Care Unit. He is trained and board certified both as a pediatric endocrinologist and pediatric intensivist, and holds the Constantine Anast MD Professorship of Pediatrics at Harvard Medical School.

Dr. Agus is engaged in clinical research activities that attempt to address unanswered questions concerning endocrine homeostasis in critically ill children, focusing on glycemic control and the use of glucocorticoids in the ICU. He completed two NHLBI/NIH R01-funded prospective, randomized clinical trials of glucose control, two of the largest RCTs in the field of pediatric critical care. The first, called SPECS involved 980 post-operative cardiac surgery patients <3 years of age at two centers. The second included 780 medical/surgical patients in 35 Pediatric ICUs across the US and Canada. Results of both trials were published in the New England Journal of Medicine. He used technology, honed over several years of research, to allow the lowest severe hypoglycemia rate in the field. He is currently one of the lead investigators organizing the NICHD/NIH-funded multicenter SHIPSS trial, Stress Hydrocortisone in Pediatric Septic Shock.